Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9844820 | 0.92 | DHFR (0.61) | DHFRTYMS | |
| SCHEMBL9844817 | 0.92 | DHFR (0.61) | DHFRTYMS | |
| SCHEMBL9844833 | 0.91 | DHFR (0.60) | DHFRTYMS | |
| SCHEMBL9564148 | 0.84 | L3MBTL1 (0.45) | DHFRTYMS | |
| SCHEMBL9564146 | 0.84 | L3MBTL1 (0.45) | DHFRTYMS | |
| SCHEMBL9844873 | 0.82 | DHFR (0.57) | DHFRTYMS | |
| SCHEMBL9844857 | 0.82 | DHFR (0.55) | DHFRTYMS | |
| SCHEMBL9564226 | 0.81 | DHFR (0.73) | DHFRTYMS | |
| SCHEMBL9844850 | 0.81 | DHFR (0.54) | DHFRTYMS | |
| SCHEMBL9844793 | 0.79 | DHFR (0.55) | DHFRTYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0549291-A1 | Thymidylate synthase inhibitors | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-06-30 | — | — | EP | disclosed |