Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KLK7 | P49862 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 3/20 | 0.40 |
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9564392 | 1.00 | MAPT (0.49) | MAPTNPC1RAB9AHTTHPGD | |
| SCHEMBL9564396 | 0.77 | ALDH1A1 (0.44) | MAPTNPC1RAB9AHPGDMEN1 | |
| SCHEMBL9564391 | 0.77 | ALDH1A1 (0.44) | MAPTNPC1RAB9AHPGDMEN1 | |
| SCHEMBL13631426 | 0.73 | HPGD (0.71) | HTTHPGDTSHRPOLBKLK7 | |
| SCHEMBL9564372 | 0.71 | KMT2A (0.43) | MAPTNPC1RAB9AHPGDPOLB | |
| SCHEMBL9564365 | 0.71 | KMT2A (0.43) | MAPTNPC1RAB9AHPGDPOLB | |
| SCHEMBL9564366 | 0.71 | GAA (0.50) | MAPTHTTHPGDTSHRPOLB | |
| SCHEMBL10874394 | 0.71 | MAPT (0.48) | MAPTNPC1RAB9AHTTHPGD | |
| SCHEMBL9564371 | 0.71 | GAA (0.50) | MAPTHTTHPGDTSHRPOLB | |
| SCHEMBL9564370 | 0.69 | GAA (0.48) | MAPTNPC1RAB9AHTTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563686-A1 | Utilization of 3 substituted amino isoxazole derivatives against endoparasites, new 3 substituted amino isoxazols and process for their preparation | BAYER AG (DE) | 1993-10-06 | — | — | EP | disclosed |