Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 6/20 | 0.37 |
| ▸ | RAB9A | P51151 | 6/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9564365 | 1.00 | KMT2A (0.43) | KMT2ATDP1POLBDAOTAS1R3 | |
| SCHEMBL9564382 | 0.84 | KMT2A (0.44) | KMT2ATDP1POLBDAOALDH1A1 | |
| SCHEMBL9564370 | 0.77 | GAA (0.48) | KMT2ATDP1POLBALDH1A1KDM4E | |
| SCHEMBL9564376 | 0.77 | GAA (0.48) | KMT2ATDP1POLBALDH1A1KDM4E | |
| SCHEMBL9564345 | 0.76 | KDR (0.34) | KMT2AALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL9564349 | 0.76 | KDR (0.34) | KMT2AALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL9564369 | 0.73 | ALDH1A1 (0.49) | KMT2AALDH1A1MAPTCASP1CASP7 | |
| SCHEMBL12124277 | 0.73 | KMT2A (0.69) | KMT2ATDP1POLBDAOTAS1R3 | |
| SCHEMBL9564389 | 0.71 | MAPT (0.49) | KMT2APOLBALDH1A1KDM4EMAPT | |
| SCHEMBL9564392 | 0.71 | MAPT (0.49) | KMT2APOLBALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563686-A1 | Utilization of 3 substituted amino isoxazole derivatives against endoparasites, new 3 substituted amino isoxazols and process for their preparation | BAYER AG (DE) | 1993-10-06 | — | — | EP | disclosed |