Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | FASN | P49327 | 1/20 | 0.34 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9564491 | 0.83 | POLB (0.54) | CA12CA9POLBALDH1A1LMNA | |
| SCHEMBL10513589 | 0.74 | PIK3CG (0.51) | POLBALDH1A1LMNAMAPTNPC1 | |
| SCHEMBL27342078 | 0.70 | KDM4E (0.41) | ALDH1A1KDM4E | |
| SCHEMBL10513596 | 0.69 | POLB (0.46) | CA12CA9POLBALDH1A1LMNA | |
| SCHEMBL10863227 | 0.69 | PIK3CG (0.51) | POLBALDH1A1LMNAMAPTNPC1 | |
| SCHEMBL10923479 | 0.67 | POLB (0.46) | CA12CA9POLBALDH1A1LMNA | |
| SCHEMBL15525167 | 0.66 | POLB (0.55) | POLBALDH1A1LMNAMAPTNPC1 | |
| SCHEMBL9564472 | 0.66 | KDM4E (0.42) | POLBALDH1A1LMNAMAPTNPC1 | |
| SCHEMBL10863231 | 0.65 | POLB (0.41) | CA12CA9POLBALDH1A1LMNA | |
| SCHEMBL9564482 | 0.64 | KDM4E (0.38) | POLBALDH1A1LMNAMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0531958-A1 | 6-Aminoquinolones, their synthesis and their use as antibacterial agents | MEDIOLANUM FARMACEUTICI S.P.A. (IT) | 1993-03-17 | — | — | EP | disclosed |