Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GALR2 | O43603 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9564442 | 0.83 | CA12 (0.41) | POLBMAPTALDH1A1LMNANPC1 | |
| SCHEMBL9564473 | 0.82 | GPR174 (0.44) | MAPTALDH1A1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL9564452 | 0.78 | NPC1 (0.53) | POLBMAPTALDH1A1LMNANPC1 | |
| SCHEMBL10473197 | 0.78 | POLB (0.71) | POLBMAPTALDH1A1LMNANPC1 | |
| SCHEMBL9564489 | 0.75 | MEN1 (0.37) | POLBMAPTALDH1A1LMNAMEN1 | |
| SCHEMBL9564507 | 0.75 | RXFP1 (0.40) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL9564450 | 0.75 | MEN1 (0.40) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL8857586 | 0.74 | POLB (0.46) | POLBMAPTALDH1A1LMNANPC1 | |
| SCHEMBL9564469 | 0.69 | LGMN (0.41) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL23037281 | 0.69 | TOP2A (0.47) | ALDH1A1NPC1KMT2ARAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0531958-A1 | 6-Aminoquinolones, their synthesis and their use as antibacterial agents | MEDIOLANUM FARMACEUTICI S.P.A. (IT) | 1993-03-17 | — | — | EP | disclosed |