Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.42 |
| ▸ | GAA | P10253 | 5/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.36 |
| ▸ | IP6K1 | Q92551 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | TOP2A | P11388 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9564482 | 0.91 | KDM4E (0.38) | KDM4EGAAHSD17B10POLBTDP1 | |
| SCHEMBL9564465 | 0.90 | HSD17B10 (0.45) | KDM4EGAAHSD17B10POLBTDP1 | |
| SCHEMBL9564467 | 0.90 | KDM4E (0.41) | KDM4EGAAHSD17B10POLBL3MBTL1 | |
| SCHEMBL9564477 | 0.86 | PIM1 (0.43) | KDM4EGAAHSD17B10POLBNR4A1 | |
| SCHEMBL9564496 | 0.83 | KCNH2 (0.38) | KDM4EGAAHSD17B10POLBNR4A1 | |
| SCHEMBL6790985 | 0.75 | ALDH1A1 (0.61) | KDM4EHSD17B10SMN1; SMN2NPSR1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6223889 | 0.74 | ALDH1A1 (0.59) | KDM4EHSD17B10SMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL11010865 | 0.71 | MEN1 (0.51) | KDM4EHSD17B10SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL27342078 | 0.70 | KDM4E (0.41) | KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL9749773 | 0.70 | KDM4E (0.42) | KDM4EHSD17B10SMN1; SMN2NPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0531958-A1 | 6-Aminoquinolones, their synthesis and their use as antibacterial agents | MEDIOLANUM FARMACEUTICI S.P.A. (IT) | 1993-03-17 | — | — | EP | disclosed |