Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.38 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9564491 | 0.78 | POLB (0.54) | NPC1POLBALDH1A1MAPTLMNA | |
| SCHEMBL10474375 | 0.77 | MAPT (0.47) | NPC1POLBALDH1A1MAPTLMNA | |
| SCHEMBL9987119 | 0.71 | MAPK1 (0.51) | POLBALDH1A1MAPTKDM4EHTT | |
| SCHEMBL28341774 | 0.66 | MAPK1 (0.53) | NPC1POLBALDH1A1MAPTKDM4E | |
| SCHEMBL23886812 | 0.66 | L3MBTL1 (0.48) | NPC1ALDH1A1MAPTLMNAKDM4E | |
| SCHEMBL30176410 | 0.66 | L3MBTL1 (0.48) | NPC1ALDH1A1MAPTLMNAKDM4E | |
| SCHEMBL22760420 | 0.66 | MAPT (0.47) | NPC1ALDH1A1MAPTKDM4ETDP1 | |
| SCHEMBL6298947 | 0.66 | NOD2 (0.68) | ALDH1A1MAPTLMNAKDM4EHTT | |
| SCHEMBL10003762 | 0.65 | POLB (0.44) | NPC1POLBMAPTLMNAKDM4E | |
| SCHEMBL10473197 | 0.65 | POLB (0.71) | NPC1POLBALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0531958-A1 | 6-Aminoquinolones, their synthesis and their use as antibacterial agents | MEDIOLANUM FARMACEUTICI S.P.A. (IT) | 1993-03-17 | — | — | EP | disclosed |