Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | ALK | Q9UM73 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9564472 | 0.90 | KDM4E (0.42) | KDM4EALDH1A1HSD17B10GAAPOLB | |
| SCHEMBL9564482 | 0.87 | KDM4E (0.38) | KDM4EALDH1A1HSD17B10GAAPOLB | |
| SCHEMBL9564465 | 0.86 | HSD17B10 (0.45) | KDM4EALDH1A1HSD17B10GAAPOLB | |
| SCHEMBL9564469 | 0.85 | LGMN (0.41) | KDM4EALDH1A1HSD17B10GAAMAPT | |
| SCHEMBL9564477 | 0.83 | PIM1 (0.43) | KDM4EALDH1A1HSD17B10GAAPOLB | |
| SCHEMBL9564496 | 0.82 | KCNH2 (0.38) | KDM4EHSD17B10GAAPOLBNR4A1 | |
| SCHEMBL9564483 | 0.79 | PIK3CA (0.37) | ALDH1A1HSD17B10MAPK1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9564479 | 0.78 | SCN5A (0.34) | KDM4EALDH1A1HSD17B10POLBMAPK1 | |
| SCHEMBL9564460 | 0.78 | LMNA (0.49) | KDM4EALDH1A1HSD17B10DRD3GAA | |
| SCHEMBL10377651 | 0.75 | ALDH1A1 (0.63) | KDM4EALDH1A1HSD17B10DRD3GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5239028-A | — | — | None | — | — | JP | disclosed |
| JP-H05239028-A | 6-AMINOQUINOLONE, ITS SYNTHESIS AND ITS USE AS ANTIBACTERIAL SUBSTANCE | MEDIOLANUM FARMACEUT SRL | 1993-09-17 | — | — | JP | disclosed |
| EP-0531958-A1 | 6-Aminoquinolones, their synthesis and their use as antibacterial agents | MEDIOLANUM FARMACEUTICI S.P.A. (IT) | 1993-03-17 | — | — | EP | disclosed |