Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 3/20 | 0.43 |
| ▸ | PIM3 | Q86V86 | 3/20 | 0.43 |
| ▸ | GSK3A | P49840 | 2/20 | 0.43 |
| ▸ | GSK3B | P49841 | 2/20 | 0.43 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.43 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.43 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | CSNK1G3 | Q9Y6M4 | 1/20 | 0.43 |
| ▸ | TOP1 | P11387 | 3/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9564482 | 0.86 | KDM4E (0.38) | PIM1PIM3GSK3AGSK3BPRKD3 | |
| SCHEMBL9564472 | 0.86 | KDM4E (0.42) | POLBALDH1A1KDM4EGAANR4A1 | |
| SCHEMBL9564467 | 0.83 | KDM4E (0.41) | POLBALDH1A1KDM4EGAANR4A1 | |
| SCHEMBL9564465 | 0.83 | HSD17B10 (0.45) | POLBALDH1A1KDM4EGAANR4A1 | |
| SCHEMBL9564496 | 0.81 | KCNH2 (0.38) | PIM1PIM3GSK3AGSK3BPRKD3 | |
| SCHEMBL6800209 | 0.70 | PIM1 (0.51) | PIM1PIM3GSK3AGSK3BPRKD3 | |
| SCHEMBL6790985 | 0.70 | ALDH1A1 (0.61) | PIM1PIM3GSK3AGSK3BPRKD3 | |
| SCHEMBL13713252 | 0.70 | PIM1 (0.51) | PIM1PIM3GSK3AGSK3BPRKD3 | |
| SCHEMBL9749773 | 0.69 | KDM4E (0.42) | PIM1PIM3GSK3AGSK3BPRKD3 | |
| Hydrochloric Acid SCHEMBL6248075 | 0.69 | KDM4E (0.60) | PIM1PIM3GSK3AGSK3BPRKD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0531958-A1 | 6-Aminoquinolones, their synthesis and their use as antibacterial agents | MEDIOLANUM FARMACEUTICI S.P.A. (IT) | 1993-03-17 | — | — | EP | disclosed |