Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.35 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.35 |
| ▸ | TOP2A | P11388 | 2/20 | 0.35 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | ALB | P02768 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.34 |
| ▸ | TUBB | P07437 | 1/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9564459 | 0.86 | MEN1 (0.40) | KDM4EMAPK1ALDH1A1HSD17B10CYP1A2 | |
| SCHEMBL8741056 | 0.81 | TOP2A (0.40) | MAPK1POLBCACNA1FCACNA1DKCNH2 | |
| SCHEMBL9564461 | 0.77 | AURKA (0.37) | MAPK1TOP2ATOP2BALDH1A1HSD17B10 | |
| Hydrochloric Acid SCHEMBL9564479 | 0.76 | SCN5A (0.34) | KDM4EMAPK1POLBKCNH2ALDH1A1 | |
| SCHEMBL10700307 | 0.75 | TOP2A (0.38) | MAPK1POLBCACNA1FCACNA1DKCNH2 | |
| SCHEMBL27741279 | 0.75 | TOP2A (0.37) | MAPK1POLBCACNA1FCACNA1DKCNH2 | |
| SCHEMBL9688753 | 0.73 | TOP2A (0.34) | MAPK1POLBCACNA1FCACNA1DKCNH2 | |
| SCHEMBL10817331 | 0.72 | TOP2A (0.47) | MAPK1POLBCACNA1FCACNA1DKCNH2 | |
| SCHEMBL9564487 | 0.71 | MEN1 (0.43) | KDM4EMAPK1TOP2ATOP2BALDH1A1 | |
| SCHEMBL9564467 | 0.70 | KDM4E (0.41) | KDM4EMAPK1POLBALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0531958-A1 | 6-Aminoquinolones, their synthesis and their use as antibacterial agents | MEDIOLANUM FARMACEUTICI S.P.A. (IT) | 1993-03-17 | — | — | EP | disclosed |