Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 8/20 | 0.36 |
| ▸ | USP2 | O75604 | 7/20 | 0.36 |
| ▸ | CASP1 | P29466 | 7/20 | 0.36 |
| ▸ | CASP7 | P55210 | 7/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.36 |
| ▸ | GLA | P06280 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9564483 | 0.83 | PIK3CA (0.37) | AURKACDK1AURKBALDH1A1CYP1A2 | |
| SCHEMBL9564474 | 0.77 | KDM4E (0.39) | ALDH1A1CYP1A2USP2CASP1CASP7 | |
| SCHEMBL9564467 | 0.70 | KDM4E (0.41) | ALDH1A1HSD17B10MEN1KMT2ATSHR | |
| SCHEMBL9564504 | 0.70 | RXFP1 (0.42) | ALDH1A1MEN1KMT2A | |
| SCHEMBL9088365 | 0.69 | MAPKAPK3 (0.44) | AURKBPIM1PIM3PIM2TOP2A | |
| Hydrochloric Acid SCHEMBL9564479 | 0.67 | SCN5A (0.34) | ALDH1A1CYP1A2USP2CASP1CASP7 | |
| SCHEMBL9805870 | 0.66 | CNR1 (0.47) | CNR2 | |
| SCHEMBL9564459 | 0.64 | MEN1 (0.40) | ALDH1A1CYP1A2USP2CASP1CASP7 | |
| SCHEMBL8741056 | 0.64 | TOP2A (0.40) | MAPK1TOP2ATOP2B | |
| SCHEMBL6801320 | 0.63 | ALDH1A1 (0.40) | ALDH1A1CYP1A2USP2CASP1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0531958-A1 | 6-Aminoquinolones, their synthesis and their use as antibacterial agents | MEDIOLANUM FARMACEUTICI S.P.A. (IT) | 1993-03-17 | — | — | EP | disclosed |