Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.47 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 5/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | STAT1 | P42224 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8572316 | 0.88 | TSHR (0.57) | ALDH1A1CSNK2A2CSNK2A1RAB9AL3MBTL1 | |
| SCHEMBL8569581 | 0.80 | ALDH1A1 (0.44) | ALDH1A1RAB9ATSHRNPC1SMN1; SMN2 | |
| SCHEMBL14647559 | 0.73 | KDM4E (0.52) | ALDH1A1RAB9ANPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL8567632 | 0.73 | TSHR (0.47) | ALDH1A1RAB9ATSHRMAPK1NPC1 | |
| SCHEMBL3368672 | 0.72 | EPHX1 (0.59) | ALDH1A1CSNK2A2CSNK2A1RAB9AL3MBTL1 | |
| SCHEMBL77674 | 0.70 | MAPK1 (0.56) | ALDH1A1CSNK2A2CSNK2A1RAB9AL3MBTL1 | |
| SCHEMBL91407 | 0.69 | TSHR (0.68) | ALDH1A1CSNK2A2CSNK2A1RAB9AL3MBTL1 | |
| SCHEMBL77077 | 0.68 | MAPK1 (0.57) | ALDH1A1CSNK2A2CSNK2A1RAB9AL3MBTL1 | |
| SCHEMBL3369754 | 0.68 | EPHX1 (0.54) | ALDH1A1CSNK2A2CSNK2A1RAB9AL3MBTL1 | |
| SCHEMBL3368234 | 0.68 | EPHX1 (0.54) | ALDH1A1CSNK2A2CSNK2A1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536900-A2 | Process for preparing 1,2,4-Thiadiazole Derivatives | KATAYAMA SEIYAKUSYO CO. Ltd. (JP) | 1993-04-14 | — | — | EP | disclosed |