Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8573320 | 0.87 | NPC1 (0.44) | ALDH1A1NPC1SMN1; SMN2MAPTRAB9A | |
| SCHEMBL6757740 | 0.86 | ALDH1A1 (0.45) | ALDH1A1NPC1SMN1; SMN2MAPTRAB9A | |
| SCHEMBL1080488 | 0.85 | ALDH1A1 (0.41) | ALDH1A1NPC1SMN1; SMN2MAPTRAB9A | |
| SCHEMBL8573205 | 0.83 | ALDH1A1 (0.50) | ALDH1A1NPC1SMN1; SMN2MAPTRAB9A | |
| SCHEMBL8568524 | 0.82 | TSHR (0.43) | ALDH1A1NPC1SMN1; SMN2MAPTRAB9A | |
| SCHEMBL8572623 | 0.80 | ALDH1A1 (0.48) | ALDH1A1NPC1SMN1; SMN2MAPTRAB9A | |
| SCHEMBL9564494 | 0.80 | ALDH1A1 (0.49) | ALDH1A1NPC1SMN1; SMN2RAB9ALMNA | |
| SCHEMBL8572006 | 0.79 | NPC1 (0.37) | ALDH1A1NPC1SMN1; SMN2MAPTRAB9A | |
| SCHEMBL14647559 | 0.74 | KDM4E (0.52) | ALDH1A1NPC1SMN1; SMN2MAPTRAB9A | |
| SCHEMBL8567632 | 0.74 | TSHR (0.47) | ALDH1A1NPC1SMN1; SMN2MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5271210-A | — | — | None | — | — | JP | disclosed |
| US-5705650-A | Process for preparing 1,2,4-thiadiazole derivatives | KATAYAMA SEIYAKUSYO CO., LTD. (JP) | 1998-01-06 | — | — | US | disclosed |
| US-5585494-A | Process for preparing 1,2,4-thiadiazole derivatives | KATAYAMA SEIYAKUSYO CO. LTD. (JP) | 1996-12-17 | — | — | US | disclosed |
| JP-H05271210-A | PRODUCTION OF THIADIAZOLE COMPOUND | KATAYAMA SEIYAKUSHIYO:KK | 1993-10-19 | — | — | JP | disclosed |
| EP-0536900-A2 | Process for preparing 1,2,4-Thiadiazole Derivatives | KATAYAMA SEIYAKUSYO CO. Ltd. (JP) | 1993-04-14 | — | — | EP | disclosed |