Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 3/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | GABBR2 | O75899 | 4/20 | 0.38 |
| ▸ | GABBR1 | Q9UBS5 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2148327 | 0.94 | BLM (0.41) | BLMDRD3GABBR2GABBR1CYP1A2 | |
| SCHEMBL2148514 | 0.93 | PAOX (0.40) | BLMDRD3GABBR2GABBR1CYP1A2 | |
| SCHEMBL2148490 | 0.93 | PAOX (0.40) | BLMDRD3GABBR2GABBR1CYP1A2 | |
| SCHEMBL2148523 | 0.88 | ANPEP (0.38) | BLMDRD3GABBR2GABBR1CYP1A2 | |
| SCHEMBL2148435 | 0.81 | ALDH1A1 (0.34) | ANPEP | |
| SCHEMBL28588396 | 0.77 | BLM (0.39) | BLMDRD3GABBR2GABBR1CYP1A2 | |
| SCHEMBL3795216 | 0.77 | BLM (0.50) | BLMDRD3GABBR2GABBR1CYP1A2 | |
| SCHEMBL2148512 | 0.77 | GABBR2 (0.36) | BLMDRD3GABBR2GABBR1CYP1A2 | |
| SCHEMBL371419 | 0.76 | BLM (0.43) | BLMDRD3GABBR2GABBR1CYP1A2 | |
| SCHEMBL2148484 | 0.76 | ANPEP (0.33) | ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0538911-A2 | Chemical prevention or reversal of cataract by phase separation inhibitors | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1993-04-28 | — | — | EP | claimed |
| EP-0316438-A1 | CHEMICAL PREVENTION OR REVERSAL OF CATARACT BY PHASE SEPARATION INHIBITORS. | MASSACHUSETTS INST TECHNOLOGY (US) | 1989-05-24 | — | — | EP | claimed |
| WO-1988009660-A2 | CHEMICAL PREVENTION OR REVERSAL OF CATARACT BY PHASE SEPARATION INHIBITORS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1988-12-15 | — | — | WO | claimed |