Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 2/20 | 1.00 |
| ▸ | GRIA2 | P42262 | 2/20 | 1.00 |
| ▸ | GRIA3 | P42263 | 2/20 | 1.00 |
| ▸ | GRIA4 | P48058 | 2/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | PARP1 | P09874 | 2/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9564554 | 0.90 | GRIA1 (0.82) | GRIA1GRIA2GRIA3GRIA4LMNA | |
| SCHEMBL9564548 | 0.82 | GRIA1 (0.70) | GRIA1GRIA2GRIA3GRIA4LMNA | |
| SCHEMBL9564526 | 0.80 | GRIA1 (0.66) | GRIA1GRIA2GRIA3GRIA4PARP1 | |
| SCHEMBL9564531 | 0.80 | GRIA1 (0.66) | GRIA1GRIA2GRIA3GRIA4PARP1 | |
| SCHEMBL9564541 | 0.78 | GRIA1 (0.63) | GRIA1GRIA2GRIA3GRIA4DAO | |
| SCHEMBL9564550 | 0.75 | GRIA1 (0.60) | GRIA1GRIA2GRIA3GRIA4LMNA | |
| SCHEMBL9564533 | 0.74 | GRIA1 (0.58) | GRIA1GRIA2GRIA3GRIA4LMNA | |
| SCHEMBL9564547 | 0.74 | GRIA1 (0.58) | GRIA1GRIA2GRIA3GRIA4MAPT | |
| SCHEMBL9564538 | 0.73 | GRIA1 (0.58) | GRIA1GRIA2GRIA3GRIA4DAO | |
| SCHEMBL8687546 | 0.72 | GRIA1 (0.56) | GRIA1GRIA2GRIA3GRIA4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542609-A1 | 3-sulfonylamino-2-(1H)-quinolinones and 7-aza derivatives as excitatory amino acids antagonists | ADIR ET COMPAGNIE (FR) | 1993-05-19 | — | — | EP | claimed |
| EP-0542609-A1 | 3-sulfonylamino-2-(1H)-quinolinones and 7-aza derivatives as excitatory amino acids antagonists | ADIR ET COMPAGNIE (FR) | 1993-05-19 | — | — | EP | disclosed |