Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 5/20 | 0.70 |
| ▸ | GRIA2 | P42262 | 5/20 | 0.70 |
| ▸ | GRIA3 | P42263 | 5/20 | 0.70 |
| ▸ | GRIA4 | P48058 | 5/20 | 0.70 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.46 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.46 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.46 |
| ▸ | GRIK4 | Q16099 | 2/20 | 0.46 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.46 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.46 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.46 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.46 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9564554 | 0.82 | GRIA1 (0.82) | GRIA1GRIA2GRIA3GRIA4MAPT | |
| SCHEMBL9564532 | 0.82 | GRIA1 (1.00) | GRIA1GRIA2GRIA3GRIA4MAPT | |
| SCHEMBL9564550 | 0.79 | GRIA1 (0.60) | GRIA1GRIA2GRIA3GRIA4MAPT | |
| SCHEMBL9564533 | 0.79 | GRIA1 (0.58) | GRIA1GRIA2GRIA3GRIA4MAPT | |
| SCHEMBL9564549 | 0.74 | GRIA1 (0.54) | GRIA1GRIA2GRIA3GRIA4MAPT | |
| SCHEMBL9564541 | 0.74 | GRIA1 (0.63) | GRIA1GRIA2GRIA3GRIA4MAPT | |
| SCHEMBL9564531 | 0.74 | GRIA1 (0.66) | GRIA1GRIA2GRIA3GRIA4MAPT | |
| SCHEMBL9564526 | 0.74 | GRIA1 (0.66) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL9564528 | 0.74 | GRIA1 (0.56) | GRIA1GRIA2GRIA3GRIA4CA2 | |
| SCHEMBL8682373 | 0.71 | GRIA2 (0.56) | GRIA1GRIA2GRIA3GRIA4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542609-A1 | 3-sulfonylamino-2-(1H)-quinolinones and 7-aza derivatives as excitatory amino acids antagonists | ADIR ET COMPAGNIE (FR) | 1993-05-19 | — | — | EP | disclosed |