Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 2/20 | 0.60 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.60 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.60 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.60 |
| ▸ | APEX1 | P27695 | 2/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | PLCG2 | P16885 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9564548 | 0.79 | GRIA1 (0.70) | GRIA1GRIA2GRIA3GRIA4MAPT | |
| SCHEMBL9564554 | 0.75 | GRIA1 (0.82) | GRIA1GRIA2GRIA3GRIA4PARP1 | |
| SCHEMBL9564532 | 0.75 | GRIA1 (1.00) | GRIA1GRIA2GRIA3GRIA4PARP1 | |
| SCHEMBL9564541 | 0.74 | GRIA1 (0.63) | GRIA1GRIA2GRIA3GRIA4MAPT | |
| SCHEMBL1370450 | 0.69 | APEX1 (0.61) | APEX1PARP1MAPTMAPK1NPC1 | |
| SCHEMBL9564555 | 0.69 | GRIA1 (0.47) | GRIA1GRIA2GRIA3GRIA4KDM4E | |
| SCHEMBL21639494 | 0.68 | APEX1 (0.68) | APEX1PARP1MAPTMAPK1NPC1 | |
| SCHEMBL9564538 | 0.68 | GRIA1 (0.58) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL28798246 | 0.67 | APEX1 (0.62) | APEX1PARP1MAPTMAPK1NPC1 | |
| SCHEMBL28592519 | 0.67 | APEX1 (0.62) | APEX1PARP1MAPTMAPK1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542609-A1 | 3-sulfonylamino-2-(1H)-quinolinones and 7-aza derivatives as excitatory amino acids antagonists | ADIR ET COMPAGNIE (FR) | 1993-05-19 | — | — | EP | disclosed |