Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK33 | Q9BYT3 | 1/20 | 0.55 |
| ▸ | BRD4 | O60885 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | DAO | P14920 | 1/20 | 0.46 |
| ▸ | DDO | Q99489 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | G6PD | P11413 | 1/20 | 0.44 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.44 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9564553 | 0.81 | BRD4 (0.53) | BRD4ALDH1A1HSD17B10KDM4ELMNA | |
| SCHEMBL6925200 | 0.80 | BCAT1 (0.54) | STK33BRD4RECQLBCAT1ALDH1A1 | |
| SCHEMBL9564525 | 0.79 | BRD4 (0.55) | BRD4ALDH1A1KMT2AMEN1NFKBIA | |
| SCHEMBL7577515 | 0.78 | SMN1; SMN2 (0.65) | RECQLALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL9564541 | 0.78 | GRIA1 (0.63) | BRD4ALDH1A1HSD17B10KDM4EKMT2A | |
| SCHEMBL16627639 | 0.74 | PYGM (0.55) | BRD4RECQLALDH1A1HSD17B10MAPK1 | |
| SCHEMBL12909532 | 0.74 | BRD4 (0.59) | BRD4ALDH1A1HSD17B10KDM4EDAO | |
| SCHEMBL5469296 | 0.73 | CDK5 (0.63) | KMT2AMEN1 | |
| SCHEMBL5514709 | 0.73 | PIK3CG (0.51) | BCAT1ALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL6295404 | 0.71 | GAA (0.64) | RECQLALDH1A1HSD17B10MAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542609-A1 | 3-sulfonylamino-2-(1H)-quinolinones and 7-aza derivatives as excitatory amino acids antagonists | ADIR ET COMPAGNIE (FR) | 1993-05-19 | — | — | EP | disclosed |