Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 1/20 | 0.47 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.47 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.47 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 5/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 9/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 8/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9564524 | 0.78 | GRIA1 (0.47) | GRIA1GRIA2GRIA3GRIA4CA2 | |
| SCHEMBL9564533 | 0.78 | GRIA1 (0.58) | GRIA1GRIA2GRIA3GRIA4CA2 | |
| SCHEMBL9564526 | 0.76 | GRIA1 (0.66) | GRIA1GRIA2GRIA3GRIA4CA2 | |
| SCHEMBL9564541 | 0.70 | GRIA1 (0.63) | GRIA1GRIA2GRIA3GRIA4CA2 | |
| SCHEMBL829912 | 0.70 | AKR1B1 (0.51) | GRIA1GRIA2GRIA3GRIA4CA2 | |
| SCHEMBL9564538 | 0.69 | GRIA1 (0.58) | GRIA1GRIA2GRIA3GRIA4PTGS1 | |
| SCHEMBL11336224 | 0.69 | CA2 (0.51) | CA2CA1PTGS1PTGS2KDM1A | |
| SCHEMBL9564550 | 0.69 | GRIA1 (0.60) | GRIA1GRIA2GRIA3GRIA4CA2 | |
| SCHEMBL11330348 | 0.68 | CA2 (0.67) | CA2CA1PTGS1PTGS2 | |
| SCHEMBL9564531 | 0.68 | GRIA1 (0.66) | GRIA1GRIA2GRIA3GRIA4CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542609-A1 | 3-sulfonylamino-2-(1H)-quinolinones and 7-aza derivatives as excitatory amino acids antagonists | ADIR ET COMPAGNIE (FR) | 1993-05-19 | — | — | EP | disclosed |