Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.50 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.50 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.50 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.50 |
| ▸ | MMP13 | P45452 | 2/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9564547 | 0.91 | GRIA1 (0.58) | SMN1; SMN2MAPK1GRIA1GRIA2GRIA3 | |
| SCHEMBL9564528 | 0.78 | GRIA1 (0.56) | GRIA1GRIA2GRIA3GRIA4KMT2A | |
| SCHEMBL9564541 | 0.76 | GRIA1 (0.63) | GRIA1GRIA2GRIA3GRIA4KMT2A | |
| SCHEMBL122373 | 0.75 | MAPK1 (0.66) | SMN1; SMN2MAPK1KMT2APKMALDH1A1 | |
| SCHEMBL11511786 | 0.74 | MAPK1 (0.64) | SMN1; SMN2MAPK1KMT2APKMALDH1A1 | |
| SCHEMBL9564533 | 0.72 | GRIA1 (0.58) | SMN1; SMN2GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL9564531 | 0.70 | GRIA1 (0.66) | GRIA1GRIA2GRIA3GRIA4KIF11 | |
| SCHEMBL9564526 | 0.70 | GRIA1 (0.66) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL6001666 | 0.70 | KDM4E (0.52) | SMN1; SMN2MAPK1MMP13KMT2AMEN1 | |
| SCHEMBL6015700 | 0.70 | MAOB (0.67) | SMN1; SMN2MMP13ROCK2ROCK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542609-A1 | 3-sulfonylamino-2-(1H)-quinolinones and 7-aza derivatives as excitatory amino acids antagonists | ADIR ET COMPAGNIE (FR) | 1993-05-19 | — | — | EP | disclosed |