Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 1/20 | 0.56 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.56 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.56 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.56 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 5/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | IDH1 | O75874 | 1/20 | 0.36 |
| ▸ | PARG | Q86W56 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9564541 | 0.82 | GRIA1 (0.63) | GRIA1GRIA2GRIA3GRIA4CA2 | |
| SCHEMBL9564533 | 0.78 | GRIA1 (0.58) | GRIA1GRIA2GRIA3GRIA4CA2 | |
| SCHEMBL9564552 | 0.78 | SMN1; SMN2 (0.54) | GRIA1GRIA2GRIA3GRIA4KMT2A | |
| SCHEMBL9564526 | 0.76 | GRIA1 (0.66) | GRIA1GRIA2GRIA3GRIA4CA2 | |
| SCHEMBL9564531 | 0.76 | GRIA1 (0.66) | GRIA1GRIA2GRIA3GRIA4SLC22A12 | |
| SCHEMBL9564538 | 0.75 | GRIA1 (0.58) | GRIA1GRIA2GRIA3GRIA4PTGS1 | |
| SCHEMBL9564548 | 0.74 | GRIA1 (0.70) | GRIA1GRIA2GRIA3GRIA4CA2 | |
| SCHEMBL9564549 | 0.74 | GRIA1 (0.54) | GRIA1GRIA2GRIA3GRIA4CA2 | |
| SCHEMBL30806289 | 0.72 | HCAR1 (0.44) | GRIA1GRIA2GRIA3GRIA4CYP19A1 | |
| SCHEMBL9564532 | 0.72 | GRIA1 (1.00) | GRIA1GRIA2GRIA3GRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542609-A1 | 3-sulfonylamino-2-(1H)-quinolinones and 7-aza derivatives as excitatory amino acids antagonists | ADIR ET COMPAGNIE (FR) | 1993-05-19 | — | — | EP | disclosed |