SCHEMBL9564607

SCHEMBL9564607

CC(=Cc1ccccc1C)CN1CCNCC1

nearest known ligand 0.48

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.48
TSHR P16473 2/20 0.43
USP2 O75604 1/20 0.43
ALOX15 P16050 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
GAA P10253 1/20 0.43
HPGD P15428 1/20 0.43
ADRB1 P08588 2/20 0.41
KDM4E B2RXH2 2/20 0.41
MAPT P10636 1/20 0.40
SIGMAR1 Q99720 1/20 0.39
HTR7 P34969 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
TDP1 Q9NUW8 2/20 0.37
ALDH1A1 P00352 2/20 0.37
SLC6A2 P23975 1/20 0.36
SLC6A4 P31645 1/20 0.36
HTT P42858 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9564609 0.84 USP2 (0.43) LMNATSHRUSP2ALOX15SMN1; SMN2
SCHEMBL3416007 0.80 TSHR (0.66) TSHRUSP2ALOX15SMN1; SMN2HPGD
SCHEMBL3416005 0.80 TSHR (0.66) TSHRUSP2ALOX15SMN1; SMN2HPGD
SCHEMBL6931654 0.77 ADRB1 (0.45) LMNATSHRADRB1SIGMAR1HTR7
SCHEMBL13452373 0.73 ALDH1A1 (0.37) TSHRUSP2ALOX15SMN1; SMN2GAA
SCHEMBL10119649 0.72 KDM1A (0.44) MAPT
SCHEMBL3414770 0.72 USP2 (0.48) TSHRUSP2ALOX15SMN1; SMN2HPGD
SCHEMBL3414767 0.72 USP2 (0.48) TSHRUSP2ALOX15SMN1; SMN2HPGD
SCHEMBL20531065 0.71 ADRB1 (0.52) LMNATSHRSMN1; SMN2ADRB1MAPT
SCHEMBL14724413 0.70 ALDH1A1 (0.45) LMNATSHRSMN1; SMN2HPGDKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0551617-A2 Cinnamyl piperazine derivatives method of manufacturing the same and agricultural/horticultural fungicides containing cinnamyl piperazine derivatives UBE INDUSTRIES, LTD. (JP) 1993-07-21 EP disclosed