Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | IDH2 | P48735 | 2/20 | 0.45 |
| ▸ | FBP1 | P09467 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.44 |
| ▸ | KCNAB1 | Q14722 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | IDH1 | O75874 | 2/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.43 |
| ▸ | FLT1 | P17948 | 1/20 | 0.43 |
| ▸ | FLT4 | P35916 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9480079 | 0.92 | MEN1 (0.48) | CA2MEN1KMT2ASLC2A1ALDH1A1 | |
| SCHEMBL9478799 | 0.90 | MEN1 (0.60) | CA2MEN1KMT2AALDH1A1IDH2 | |
| SCHEMBL9476125 | 0.90 | EPHX1 (0.47) | CA2MEN1KMT2ASLC2A1ALDH1A1 | |
| SCHEMBL7983130 | 0.88 | KCNA1 (0.50) | CA2MEN1KMT2AALDH1A1FBP1 | |
| SCHEMBL9478434 | 0.87 | MEN1 (0.48) | CA2MEN1KMT2AALDH1A1FBP1 | |
| SCHEMBL9478350 | 0.87 | MEN1 (0.45) | CA2MEN1KMT2AALDH1A1FBP1 | |
| SCHEMBL9478180 | 0.87 | CA2 (0.44) | CA2MEN1KMT2AFBP1KCNA1 | |
| SCHEMBL9477511 | 0.85 | TP53 (0.56) | CA2MEN1KMT2AIDH2FBP1 | |
| SCHEMBL9478322 | 0.85 | CNR2 (0.43) | CA2MEN1KMT2AFBP1KCNA1 | |
| SCHEMBL9478804 | 0.85 | MEN1 (0.48) | CA2MEN1KMT2AALDH1A1FBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0546763-A1 | Antitumor compositions and methods of treatment | ELI LILLY AND COMPANY (US) | 1993-06-16 | — | — | EP | disclosed |