Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.62 |
| ▸ | NPC1 | O15118 | 5/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | MAOA | P21397 | 2/20 | 0.62 |
| ▸ | GMNN | O75496 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | HTR1A | P08908 | 1/20 | 0.62 |
| ▸ | THRB | P10828 | 1/20 | 0.62 |
| ▸ | PIM1 | P11309 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.62 |
| ▸ | HTR2A | P28223 | 1/20 | 0.62 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.62 |
| ▸ | CCKBR | P32239 | 1/20 | 0.62 |
| ▸ | MC4R | P32245 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8813080 | 0.83 | MAPT (0.49) | RAB9ANPC1SMN1; SMN2HTTLMNA | |
| SCHEMBL6230239 | 0.83 | RAB9A (0.72) | RAB9ANPC1SMN1; SMN2HTTMAOA | |
| SCHEMBL19376893 | 0.82 | RAB9A (0.59) | RAB9ANPC1SMN1; SMN2HTTLMNA | |
| SCHEMBL19402543 | 0.82 | KMT2A (0.67) | RAB9ASMN1; SMN2HTTLMNAMAPT | |
| SCHEMBL8812360 | 0.81 | RAB9A (0.70) | RAB9ANPC1SMN1; SMN2HTTMAOA | |
| SCHEMBL8808712 | 0.81 | MAPT (0.52) | RAB9ANPC1SMN1; SMN2HTTMAOA | |
| SCHEMBL20456411 | 0.80 | RAB9A (0.68) | RAB9ANPC1SMN1; SMN2HTTMAOA | |
| SCHEMBL11441650 | 0.80 | RAB9A (0.72) | RAB9ANPC1SMN1; SMN2HTTMAOA | |
| SCHEMBL6415832 | 0.80 | RAB9A (0.72) | RAB9ANPC1SMN1; SMN2HTTMAOA | |
| SCHEMBL8941902 | 0.80 | NAMPT (0.49) | RAB9ANPC1SMN1; SMN2HTTMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0573318-A1 | Phenyl carboxamide isoxazole derivatives and salts, process for their preparation and the new intermediates thereof. Their use as pharmaceuticals and pharmaceutical compositions containing them | ROUSSEL UCLAF (FR) | 1993-12-08 | — | — | EP | disclosed |