Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 14/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 13/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 9/20 | 0.37 |
| ▸ | USP2 | O75604 | 8/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 9/20 | 0.37 |
| ▸ | CASP1 | P29466 | 7/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 7/20 | 0.37 |
| ▸ | CASP7 | P55210 | 6/20 | 0.37 |
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 2/20 | 0.36 |
| ▸ | SSTR5 | P35346 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10753371 | 0.87 | SLC6A9 (0.49) | SLC6A9MEN1KMT2AMAPK1SSTR5 | |
| SCHEMBL10877241 | 0.86 | CYP1A2 (0.36) | CYP1A2CYP3A4ALDH1A1HSD17B10USP2 | |
| SCHEMBL9565012 | 0.86 | SSTR5 (0.39) | CYP1A2CYP3A4ALDH1A1HSD17B10USP2 | |
| SCHEMBL9564788 | 0.86 | ALDH1A1 (0.38) | CYP1A2CYP3A4ALDH1A1HSD17B10USP2 | |
| SCHEMBL9564960 | 0.84 | CYP1A2 (0.43) | CYP1A2CYP3A4ALDH1A1HSD17B10USP2 | |
| SCHEMBL9740847 | 0.82 | SSTR5 (0.54) | CYP1A2CYP3A4HSD17B10USP2CYP2D6 | |
| SCHEMBL9629312 | 0.82 | SLC6A9 (0.47) | SLC6A9SSTR5KCNH2MAPTTP53 | |
| SCHEMBL9564897 | 0.81 | SSTR5 (0.54) | CYP1A2CYP3A4ALDH1A1USP2CYP2D6 | |
| SCHEMBL9564849 | 0.80 | SMN1; SMN2 (0.50) | ALDH1A1HSD17B10CYP2D6HPGDTSHR | |
| Water SCHEMBL9564898 | 0.79 | ALDH1A1 (0.42) | CYP1A2CYP3A4ALDH1A1HSD17B10USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5258380-A | Antiallergens, antihistamines | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-11-02 | — | — | US | disclosed |
| US-5041448-A | Antiallergens | JANSSEN PHARMACEUTICA N.V. (BE) | 1991-08-20 | — | — | US | disclosed |