Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 3/20 | 0.43 |
| ▸ | HRH1 | P35367 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 11/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 3/20 | 0.40 |
| ▸ | DRD4 | P21917 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MLNR | O43193 | 1/20 | 0.40 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.40 |
| ▸ | EED | O75530 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HLA-A | P04439 | 1/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9564929 | 0.90 | SSTR5 (0.57) | SSTR5HRH1KCNH2NR4A2HTR2A | |
| SCHEMBL9565012 | 0.90 | SSTR5 (0.39) | SSTR5HRH1KCNH2NR4A2HTR2A | |
| SCHEMBL9564906 | 0.90 | SSTR5 (0.39) | SSTR5HRH1KCNH2NR4A2HTR2A | |
| SCHEMBL9564808 | 0.88 | HTR2A (0.38) | SSTR5HRH1KCNH2NR4A2HTR2A | |
| SCHEMBL9565053 | 0.88 | KCNH2 (0.57) | SSTR5HRH1KCNH2NR4A2HTR2A | |
| SCHEMBL9564782 | 0.84 | KCNH2 (0.45) | HRH1KCNH2NR4A2MEN1USP2 | |
| SCHEMBL9604063 | 0.83 | HRH1 (0.36) | SSTR5HRH1KCNH2NR4A2HTR2A | |
| SCHEMBL9866590 | 0.81 | OPRM1 (0.43) | SSTR5HRH1KCNH2DRD4MEN1 | |
| SCHEMBL9602879 | 0.81 | NOS2 (0.56) | MEN1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL9699544 | 0.80 | HRH1 (0.47) | SSTR5HRH1KCNH2NR4A2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5258380-A | Antiallergens, antihistamines | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-11-02 | — | — | US | disclosed |
| US-5041448-A | Antiallergens | JANSSEN PHARMACEUTICA N.V. (BE) | 1991-08-20 | — | — | US | disclosed |
| EP-0206415-A2 | (4-Piperidinylmethyl and -hetero)purines | JANSSEN PHARMACEUTICA N.V. (BE) | 1986-12-30 | — | — | EP | disclosed |