Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 4/20 | 0.37 |
| ▸ | GABRD | O14764 | 4/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.37 |
| ▸ | GABRA4 | P48169 | 4/20 | 0.37 |
| ▸ | GABRE | P78334 | 4/20 | 0.37 |
| ▸ | GABRA6 | Q16445 | 4/20 | 0.37 |
| ▸ | GABRG1 | Q8N1C3 | 4/20 | 0.37 |
| ▸ | GABRG3 | Q99928 | 4/20 | 0.37 |
| ▸ | GABRQ | Q9UN88 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | KDM6B | O15054 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9564859 | 0.81 | XPO1 (0.46) | KDM4EASPH | |
| SCHEMBL21341341 | 0.81 | HPGD (0.39) | HPGDGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL1015354 | 0.81 | HPGD (0.42) | HPGDGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL8398359 | 0.79 | NFKB1 (0.43) | HPGDGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL4900420 | 0.77 | KDM4E (0.55) | HPGDKDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL8546294 | 0.75 | HPGD (0.59) | HPGDGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL152156 | 0.74 | HPGD (0.40) | HPGDGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL9564909 | 0.74 | — | — | |
| SCHEMBL15483441 | 0.72 | ALDH1A1 (0.36) | KDM4EALDH1A1TDP1 | |
| Water SCHEMBL2745045 | 0.72 | HPGD (0.39) | HPGDGABRPGABRDGABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0569912-A1 | 4-alkyl-substituted pyrimidine-5-carboxanilides, process for their preparation, compositions containing them and their use as fungicides | Hoechst Schering AgrEvo GmbH (DE) | 1993-11-18 | — | — | EP | disclosed |