Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9565039 | 1.00 | LMNA (0.33) | LMNAMAPK1TDP2ALDH1A1POLB | |
| SCHEMBL9565042 | 1.00 | LMNA (0.33) | LMNAMAPK1TDP2ALDH1A1POLB | |
| SCHEMBL9565067 | 0.84 | ABCC9 (0.34) | LMNA | |
| SCHEMBL9565108 | 0.84 | ABCC9 (0.34) | LMNA | |
| SCHEMBL9565070 | 0.84 | ABCC9 (0.34) | LMNA | |
| SCHEMBL9565065 | 0.80 | TP53 (0.34) | LMNAMAPK1TDP2ALDH1A1CA1 | |
| SCHEMBL9565062 | 0.80 | TP53 (0.34) | LMNAMAPK1TDP2ALDH1A1CA1 | |
| SCHEMBL9565063 | 0.80 | TP53 (0.34) | LMNAMAPK1TDP2ALDH1A1CA1 | |
| SCHEMBL7330531 | 0.76 | ABCC9 (0.38) | — | |
| SCHEMBL9564975 | 0.70 | MAPK1 (0.34) | MAPK1ALDH1A1CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0525768-A1 | Tetralones with pharmacological activity | J. URIACH & CIA. S.A. (ES) | 1993-02-03 | — | — | EP | disclosed |