Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 9/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.31 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.31 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.30 |
| ▸ | KCNE1 | P15382 | 3/20 | 0.30 |
| ▸ | KCNQ1 | P51787 | 3/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | KCND3 | Q9UK17 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9565070 | 1.00 | ABCC9 (0.34) | ABCC9KDM4EABCC8KCNJ11KCNJ8 | |
| SCHEMBL9565108 | 1.00 | ABCC9 (0.34) | ABCC9KDM4EABCC8KCNJ11KCNJ8 | |
| SCHEMBL9565039 | 0.84 | LMNA (0.33) | LMNA | |
| SCHEMBL9565036 | 0.84 | LMNA (0.33) | LMNA | |
| SCHEMBL9565042 | 0.84 | LMNA (0.33) | LMNA | |
| SCHEMBL9565078 | 0.81 | ABCC9 (0.38) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL9565076 | 0.81 | ABCC9 (0.38) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL9565074 | 0.81 | ABCC9 (0.38) | ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL9565086 | 0.78 | ABCC9 (0.35) | ABCC9KDM4ECYP3A4 | |
| SCHEMBL9565085 | 0.78 | ABCC9 (0.35) | ABCC9KDM4ECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0525768-A1 | Tetralones with pharmacological activity | J. URIACH & CIA. S.A. (ES) | 1993-02-03 | — | — | EP | claimed |
| EP-0525768-A1 | Tetralones with pharmacological activity | J. URIACH & CIA. S.A. (ES) | 1993-02-03 | — | — | EP | disclosed |