Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 9/20 | 0.48 |
| ▸ | ATF1 | P18846 | 8/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | XPO1 | O14980 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | JUN | P05412 | 2/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.39 |
| ▸ | RELA | Q04206 | 2/20 | 0.39 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9564908 | 0.87 | NFKB1 (0.63) | NFKB1ATF1XPO1JUNNFKB2 | |
| SCHEMBL9564837 | 0.85 | NFKB1 (0.54) | NFKB1ATF1XPO1MAPTNPSR1 | |
| SCHEMBL9564867 | 0.74 | ATF1 (0.48) | NFKB1ATF1XPO1MAPTJUN | |
| SCHEMBL9564940 | 0.70 | NFKB1 (0.43) | NFKB1ATF1XPO1MAPTSMN1; SMN2 | |
| SCHEMBL3381287 | 0.68 | CNR2 (0.49) | NFKB1ATF1 | |
| SCHEMBL5791566 | 0.67 | CNR2 (0.61) | — | |
| SCHEMBL1759818 | 0.67 | MAPT (0.53) | NFKB1ATF1MAPTJUNNFKB2 | |
| SCHEMBL27471255 | 0.67 | NFKB1 (0.46) | NFKB1ATF1XPO1JUNNFKB2 | |
| SCHEMBL3377570 | 0.66 | CNR2 (0.61) | — | |
| SCHEMBL5788577 | 0.66 | CNR2 (0.61) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0569912-A1 | 4-alkyl-substituted pyrimidine-5-carboxanilides, process for their preparation, compositions containing them and their use as fungicides | Hoechst Schering AgrEvo GmbH (DE) | 1993-11-18 | — | — | EP | disclosed |