Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATF1 | P18846 | 6/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 6/20 | 0.48 |
| ▸ | XPO1 | O14980 | 4/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | JUN | P05412 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.42 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.42 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.42 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | CDK8 | P49336 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9564908 | 0.86 | NFKB1 (0.63) | ATF1NFKB1XPO1JUNNFKB2 | |
| SCHEMBL9564940 | 0.78 | NFKB1 (0.43) | ATF1NFKB1XPO1JUNNFKB2 | |
| SCHEMBL9564837 | 0.77 | NFKB1 (0.54) | ATF1NFKB1XPO1JUNNFKB2 | |
| SCHEMBL9565061 | 0.74 | NFKB1 (0.48) | ATF1NFKB1XPO1JUNNFKB2 | |
| SCHEMBL3380884 | 0.72 | CNR2 (0.58) | — | |
| SCHEMBL3382843 | 0.72 | CNR2 (0.58) | — | |
| SCHEMBL2481483 | 0.72 | NFKB1 (0.46) | ATF1NFKB1XPO1JUNNFKB2 | |
| SCHEMBL3129046 | 0.72 | XPO1 (0.48) | ATF1NFKB1XPO1JUNNFKB2 | |
| SCHEMBL3379885 | 0.72 | CNR2 (0.58) | — | |
| SCHEMBL27471255 | 0.71 | NFKB1 (0.46) | ATF1NFKB1XPO1JUNNFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0569912-A1 | 4-alkyl-substituted pyrimidine-5-carboxanilides, process for their preparation, compositions containing them and their use as fungicides | Hoechst Schering AgrEvo GmbH (DE) | 1993-11-18 | — | — | EP | disclosed |