Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 16/20 | 0.63 |
| ▸ | ATF1 | P18846 | 11/20 | 0.63 |
| ▸ | JUN | P05412 | 6/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 6/20 | 0.51 |
| ▸ | RELA | Q04206 | 6/20 | 0.51 |
| ▸ | XPO1 | O14980 | 5/20 | 0.51 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9564837 | 0.90 | NFKB1 (0.54) | NFKB1ATF1JUNNFKB2RELA | |
| SCHEMBL9565061 | 0.87 | NFKB1 (0.48) | NFKB1ATF1JUNNFKB2RELA | |
| SCHEMBL9564867 | 0.86 | ATF1 (0.48) | NFKB1ATF1JUNNFKB2RELA | |
| SCHEMBL9564940 | 0.79 | NFKB1 (0.43) | NFKB1ATF1JUNNFKB2RELA | |
| SCHEMBL3129046 | 0.78 | XPO1 (0.48) | NFKB1ATF1JUNNFKB2RELA | |
| SCHEMBL2481483 | 0.78 | NFKB1 (0.46) | NFKB1ATF1JUNNFKB2RELA | |
| SCHEMBL27471255 | 0.76 | NFKB1 (0.46) | NFKB1ATF1JUNNFKB2RELA | |
| SCHEMBL9564818 | 0.76 | NFKB1 (0.40) | NFKB1ATF1JUNNFKB2RELA | |
| SCHEMBL3381287 | 0.72 | CNR2 (0.49) | NFKB1ATF1 | |
| SCHEMBL5791566 | 0.71 | CNR2 (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0569912-A1 | 4-alkyl-substituted pyrimidine-5-carboxanilides, process for their preparation, compositions containing them and their use as fungicides | Hoechst Schering AgrEvo GmbH (DE) | 1993-11-18 | — | — | EP | disclosed |