Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MDH2 | P40926 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL98338 | 0.88 | MAPT (0.54) | SMN1; SMN2L3MBTL1MAPTCYP2C9CYP2C19 | |
| SCHEMBL29498305 | 0.88 | MAPT (0.54) | SMN1; SMN2L3MBTL1MAPTCYP2C9CYP2C19 | |
| SCHEMBL1205431 | 0.85 | SMN1; SMN2 (0.41) | SMN1; SMN2L3MBTL1MAPTCYP2C9CYP2C19 | |
| SCHEMBL18993738 | 0.85 | SMN1; SMN2 (0.41) | SMN1; SMN2L3MBTL1MAPTCYP2C9CYP2C19 | |
| SCHEMBL867483 | 0.85 | SMN1; SMN2 (0.41) | SMN1; SMN2L3MBTL1MAPTCYP2C9CYP2C19 | |
| SCHEMBL18993737 | 0.85 | SMN1; SMN2 (0.41) | SMN1; SMN2L3MBTL1MAPTCYP2C9CYP2C19 | |
| SCHEMBL99439 | 0.85 | HPGDS (0.44) | SMN1; SMN2L3MBTL1MAPTCYP2C9CYP2C19 | |
| SCHEMBL28694265 | 0.84 | MAPT (0.43) | SMN1; SMN2L3MBTL1MAPTCYP2C9CYP2C19 | |
| SCHEMBL9652415 | 0.82 | ADRB2 (0.44) | SRD5A2ADORA3PIK3CGMCL1 | |
| SCHEMBL28690748 | 0.81 | L3MBTL1 (0.40) | SMN1; SMN2L3MBTL1MAPTCYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0544958-A1 | Cephalosporin compounds and processes for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1993-06-09 | — | — | EP | disclosed |