Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | WDR5 | P61964 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | LDHA | P00338 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16292878 | 0.83 | KDM4E (0.38) | KDM4EHSD17B10HPGDKMT2AALDH1A1 | |
| SCHEMBL5353695 | 0.82 | KDM4E (0.36) | KDM4EHSD17B10HPGDKMT2AALDH1A1 | |
| SCHEMBL547449 | 0.82 | KDM4E (0.45) | KDM4EHSD17B10HPGDKMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL11395268 | 0.80 | LDHA (0.44) | KDM4EHSD17B10HPGDKMT2AALDH1A1 | |
| SCHEMBL826674 | 0.80 | KDM4E (0.35) | KDM4EHSD17B10HPGDKMT2AALDH1A1 | |
| SCHEMBL112635 | 0.80 | MAPT (0.42) | KDM4EHSD17B10HPGDKMT2AALDH1A1 | |
| SCHEMBL3383913 | 0.80 | KDM4E (0.35) | KDM4EHSD17B10HPGDKMT2AALDH1A1 | |
| SCHEMBL649403 | 0.80 | ALDH1A1 (0.41) | KDM4EHSD17B10HPGDKMT2AALDH1A1 | |
| SCHEMBL5309791 | 0.80 | CA12 (0.37) | KDM4EHSD17B10HPGDKMT2AALDH1A1 | |
| SCHEMBL10499246 | 0.79 | KDM4E (0.36) | KDM4EHSD17B10HPGDKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0547514-A2 | Imidazopyridine derivatives with angiotensin-II antagonist properties | MERCK PATENT GmbH (DE) | 1993-06-23 | — | — | EP | disclosed |