SCHEMBL9565307

SCHEMBL9565307

C=CC/C=C/CC(O)C(=O)O

nearest known ligand 0.37

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.37
OR51E2 Q9H255 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.36
TET2 Q6N021 6/20 0.35
TET3 O43151 2/20 0.35
TET1 Q8NFU7 1/20 0.35
GRIK1 P39086 2/20 0.34
GRIK2 Q13002 2/20 0.34
KDM4A O75164 2/20 0.33
KDM4C Q9H3R0 2/20 0.33
KDM2A Q9Y2K7 2/20 0.33
CPA1 P15085 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9565309 1.00 CYP2C19 (0.37) CYP2C19OR51E2SMN1; SMN2TET2TET3
SCHEMBL4079703 0.79
SCHEMBL246812 0.79
SCHEMBL5674658 0.79
SCHEMBL9565299 0.78 MAPT (0.44) SMN1; SMN2
SCHEMBL9565295 0.78 MAPT (0.44) SMN1; SMN2
SCHEMBL9565306 0.78 MAPT (0.39) OR51E2SMN1; SMN2TET2TET3TET1
SCHEMBL9565305 0.78 MAPT (0.39) OR51E2SMN1; SMN2TET2TET3TET1
SCHEMBL5004152 0.77 CYP2C19 (0.36) CYP2C19GRIK1GRIK2CPA1
SCHEMBL5004153 0.77 CYP2C19 (0.36) CYP2C19GRIK1GRIK2CPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0568307-A1 Cosmetic composition containing alpha hydroxy carboxylic acids as preservatives UNILEVER PLC (GB) 1993-11-03 EP claimed
US-5108751-A COSMETIC COMPOSITION COMPRISING 2-HYDROXYALKENOIC ACIDS OR A MIXTURE THEREOF CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO, INC. (US) 1992-04-28 US claimed
EP-0442708-A2 Cosmetic composition UNILEVER PLC (GB) 1991-08-21 EP claimed
US-12082582-B2 Synergistic preservative compositions, process for preparing the same and method of use thereof ISP INVESTMENTS LLC (US) 2024-09-10 US disclosed
CN-113301802-B Synergistic preservative compositions, methods of making and methods of use thereof ISP投资有限公司 2023-08-25 CN disclosed
CN-107613767-B Synergistic preservative composition ISP投资有限公司 2022-06-21 CN disclosed
US-20220030862-A1 SYNERGISTIC PRESERVATIVE COMPOSITIONS, PROCESS FOR PREPARING THE SAME AND METHOD OF USE THEREOF ISP INVESTMENTS LLC (US) 2022-02-03 US disclosed
EP-3886582-A1 SYNERGISTIC PRESERVATIVE COMPOSITIONS, PROCESS FOR PREPARING THE SAME AND METHOD OF USE THEREOF ISP Investments LLC (US) 2021-10-06 EP disclosed
CN-113301802-A Synergistic preservative compositions, methods of making and methods of using the same ISP投资有限公司 2021-08-24 CN disclosed
WO-2020113211-A1 SYNERGISTIC PRESERVATIVE COMPOSITIONS, PROCESS FOR PREPARING THE SAME AND METHOD OF USE THEREOF ISP INVESTMENTS LLC (US) 2020-06-04 WO disclosed
US-20180092357-A1 SYNERGISTIC PRESERVATIVE COMPOSITIONS ISP INVESTMENTS LLC (US) 2018-04-05 US disclosed
EP-3288380-A1 SYNERGISTIC PRESERVATIVE COMPOSITIONS ISP Investments LLC (US) 2018-03-07 EP disclosed
WO-2016164555-A1 SYNERGISTIC PRESERVATIVE COMPOSITIONS ISP INVESTMENTS INC. (US) 2016-10-13 WO disclosed
EP-0568307-A1 Cosmetic composition containing alpha hydroxy carboxylic acids as preservatives UNILEVER PLC (GB) 1993-11-03 EP disclosed
US-5227503-A 2-Hydroxyalkenoic acids CHESEBROUGH POND'S USA CO., DIVISION OF CONOPCO, INC. (US) 1993-07-13 US disclosed
US-5108751-A COSMETIC COMPOSITION COMPRISING 2-HYDROXYALKENOIC ACIDS OR A MIXTURE THEREOF CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO, INC. (US) 1992-04-28 US disclosed
EP-0442708-A2 Cosmetic composition UNILEVER PLC (GB) 1991-08-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12082582-B2 Synergistic preservative compositions, process for preparing the same and method of use thereof HPD, EBP, TET1 CYP2C19 574/4885OR51E2 1309/4885SMN1; SMN2 3656/4885
US-20180092357-A1 SYNERGISTIC PRESERVATIVE COMPOSITIONS PIEZO1, CASP1, PRNP CYP2C19 111/4885OR51E2 891/4885SMN1; SMN2 1139/4885
US-20220030862-A1 SYNERGISTIC PRESERVATIVE COMPOSITIONS, PROCESS FOR PREPARING THE SAME AND METHOD OF USE THEREOF HPD, EBP, TET1 CYP2C19 574/4885OR51E2 1309/4885SMN1; SMN2 3656/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.