Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 3/20 | 0.60 |
| ▸ | ANPEP | P15144 | 2/20 | 0.39 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.33 |
| ▸ | CHKA | P35790 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.31 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9175624 | 0.98 | FDPS (0.58) | FDPSANPEPERAP2CA2CA12 | |
| SCHEMBL3277730 | 0.98 | FDPS (0.58) | FDPSANPEPERAP2CA2CA12 | |
| SCHEMBL9601894 | 0.98 | FDPS (0.58) | FDPSANPEPERAP2CA2CA12 | |
| SCHEMBL12250790 | 0.86 | FDPS (0.50) | FDPSANPEPERAP2CA2CA12 | |
| SCHEMBL9601881 | 0.86 | FDPS (0.45) | FDPSANPEPERAP2CA2CA12 | |
| SCHEMBL3080928 | 0.82 | FDPS (0.75) | FDPSANPEPERAP2 | |
| SCHEMBL203348 | 0.82 | FDPS (0.75) | FDPSANPEPERAP2 | |
| SCHEMBL898693 | 0.82 | FDPS (0.75) | FDPSANPEPERAP2 | |
| SCHEMBL6668799 | 0.78 | FDPS (0.39) | FDPSANPEPERAP2 | |
| SCHEMBL2203676 | 0.77 | FDPS (0.85) | FDPSANPEPERAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0561296-A1 | Cyclic aminomethylene bisphosphonate derivatives | HOECHST JAPAN LIMITED (JP) | 1993-09-22 | — | — | EP | disclosed |