SCHEMBL898693

SCHEMBL898693

O=P(O)(O)C(N1CCN(C(P(=O)(O)O)P(=O)(O)O)CCN(C(P(=O)(O)O)P(=O)(O)O)CCN(C(P(=O)(O)O)P(=O)(O)O)CC1)P(=O)(O)O

nearest known ligand 0.75

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
FDPS P14324 3/20 0.75
ANPEP P15144 2/20 0.33
ERAP2 Q6P179 1/20 0.33
KDM4E B2RXH2 1/20 0.30
MMP2 P08253 1/20 0.30
THRB P10828 1/20 0.30
MAPK1 P28482 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3080928 1.00 FDPS (0.75) FDPSANPEPERAP2KDM4EMMP2
SCHEMBL203348 1.00 FDPS (0.75) FDPSANPEPERAP2KDM4EMMP2
SCHEMBL9356971 0.89 FDPS (0.62) FDPS
SCHEMBL2203676 0.88 FDPS (0.85) FDPSANPEPERAP2MMP2
SCHEMBL26029597 0.87 FDPS (0.60) FDPS
SCHEMBL2472093 0.86 FDPS (1.00) FDPSANPEPERAP2MMP2
N-(Hexamethyleneimino)Methylenebisphosphonic Acid SCHEMBL12309768 0.86 FDPS (1.00) FDPSANPEPERAP2MMP2
SCHEMBL9565325 0.82 FDPS (0.60) FDPSANPEPERAP2
Thiomorpholinomethylenediphosphonic Acid SCHEMBL1471965 0.82 FDPS (1.00) FDPS
Morpholinomethylenediphosphonic Acid SCHEMBL3058156 0.82 FDPS (0.60) FDPSANPEPKDM4EMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 482 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260137821-A1 PEPTIDE STRUCTURE TARGETING CARBONIC DEHYDROGENASE IX AND USE THEREOF C-BIOMEX CO., LTD. (KR) 2026-05-21 US claimed
EP-4694940-A1 STEAP2-TARGETED COMPOUNDS AND USE THEREOF Astrazeneca AB (SE) 2026-02-18 EP claimed
US-12486304-B2 Peptide ligand targeting carbonic anhydrase IX, peptide construct comprising same, and uses thereof C-BIOMEX CO., LTD. (KR) 2025-12-02 US claimed
US-20250270257-A1 PEPTIDE LIGAND TARGETING CARBONIC ANHYDRASE IX, PEPTIDE CONSTRUCT COMPRISING SAME, AND USES THEREOF C-BIOMEX CO., LTD. (KR) 2025-08-28 US claimed
US-20250121104-A1 EGFR-CMET-TARGETED COMPOUNDS AND USES THEREOF ASTRAZENECA UK LIMITED (GB) 2025-04-17 US claimed
US-20250064996-A1 STABILIZED COMPOSITIONS OF RADIONUCLIDES AND USES THEREOF RAYZEBIO, INC. 2025-02-27 US claimed
WO-2024216389-A9 CLAUDIN 18.2-TARGETED COMPOUNDS AND USES THEREOF Fusion Pharmaceuticals Inc. (CA) 2025-01-23 WO claimed
US-20250001019-A1 METHODS OF TREATING CANCER Fusion Pharmaceuticals Inc. (CA) 2025-01-02 US claimed
US-20240408249-A1 EGFRVIII-TARGETED COMPOUNDS AND USES THEREOF NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2024-12-12 US claimed
EP-4452954-A2 EGFR-CMET-TARGETED COMPOUNDS AND USES THEREOF Fusion Pharmaceuticals Inc. (CA) 2024-10-30 EP claimed
US-5318772-A Polyaminemethylenephosphonic acids of diethylenediamine, norbornanediamne, 1,4,7,10-tetraazacyclododecane, 3,6,9,15-tetraazabicyclo(9.3.1)pentadecatriene or 1,4,7-triazanonane and a suitable vehicle THE DOW CHEMICAL COMPANY (US) 1994-06-07 US claimed
US-5300281-A Radiolabeled compositions containing a calcific matrix and their use for treatment of arthritis THE DOW CHEMICAL COMPANY (US) 1994-04-05 US claimed
WO-1993011741-A1 ORAL COMPOSITIONS FOR INHIBITING PLAQUE AND CALCULUS FORMATION THE DOW CHEMICAL COMPANY (US) 1993-06-24 WO claimed
EP-0468634-A1 The use of macrocyclic aminophosphonic acid complexes as imaging agents THE DOW CHEMICAL COMPANY (US) 1992-01-29 EP claimed
US-5064633-A Macrocyclic aminophosphonic acid complexes, their formulations and use THE DOW CHEMICAL COMPANY (US) 1991-11-12 US claimed
EP-0408701-A4 MACROCYCLIC AMINOPHOSPHONIC ACID COMPLEXES, THEIR PREPARATION, FORMULATIONS AND USE 1991-07-31 EP claimed
EP-0411941-A2 Process for purifying aminomethylenephosphonic acids THE DOW CHEMICAL COMPANY (US) 1991-02-06 EP claimed
EP-0408701-A1 MACROCYCLIC AMINOPHOSPHONIC ACID COMPLEXES, THEIR PREPARATION, FORMULATIONS AND USE. DOW CHEMICAL CO (US) 1991-01-23 EP claimed
WO-1990006776-A1 MACROCYCLIC AMINOPHOSPHONIC ACID COMPLEXES, THEIR PREPARATION, FORMULATIONS AND USE THE DOW CHEMICAL COMPANY (US) 1990-06-28 WO claimed
US-4937333-A Method for purifying aminomethylenephosphonic acids for pharmaceutical use THE DOW CHEMICAL COMPANY (US) 1990-06-26 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250270257-A1 PEPTIDE LIGAND TARGETING CARBONIC ANHYDRASE IX, PEPTIDE CONSTRUCT COMPRISING SAME, AND USES THEREOF CA9, CA4, CA12 FDPS 2049/4885ANPEP 14/4885ERAP2 216/4885
US-20240408249-A1 EGFRVIII-TARGETED COMPOUNDS AND USES THEREOF EGFR, ERBB3, ERBB2 FDPS 4758/4885ANPEP 275/4885ERAP2 1317/4885
US-12486304-B2 Peptide ligand targeting carbonic anhydrase IX, peptide construct comprising same, and uses thereof CA9, CA4, CA12 FDPS 2049/4885ANPEP 14/4885ERAP2 216/4885
US-20250064996-A1 STABILIZED COMPOSITIONS OF RADIONUCLIDES AND USES THEREOF TFRC, SLC39A14, EGFR FDPS 2929/4885ANPEP 104/4885ERAP2 733/4885
US-20260137821-A1 PEPTIDE STRUCTURE TARGETING CARBONIC DEHYDROGENASE IX AND USE THEREOF CA5A, CA1, CA9 FDPS 1487/4885ANPEP 159/4885ERAP2 677/4885
US-20250001019-A1 METHODS OF TREATING CANCER IGF1R, IGFBP1, IGFBP2 FDPS 4806/4885ANPEP 728/4885ERAP2 2359/4885
US-20250121104-A1 EGFR-CMET-TARGETED COMPOUNDS AND USES THEREOF EGFR, ERBB2, ERBB4 FDPS 4681/4885ANPEP 213/4885ERAP2 1078/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.