SCHEMBL9565535

SCHEMBL9565535

CCNc1cccc2c1Cc1cc(Cl)ccc1-2

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.51
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA4 P22748 1/20 0.40
CA6 P23280 1/20 0.40
ACHE P22303 1/20 0.36
METAP1 P53582 1/20 0.36
KMT2A Q03164 2/20 0.35
MEN1 O00255 1/20 0.35
USP2 O75604 1/20 0.35
CASP1 P29466 1/20 0.35
BRCA1 P38398 1/20 0.35
CASP7 P55210 1/20 0.35
EGFR P00533 1/20 0.35
ITGA1 P56199 1/20 0.34
EIF2AK1 Q9BQI3 1/20 0.34
SLC1A3 P43003 1/20 0.33
SLC1A2 P43004 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8523597 0.82 NPC1 (0.58) NPC1RAB9ACA1CA2CA4
SCHEMBL28941745 0.75 HSP90AA1 (0.59) HSP90AA1NPC1RAB9ACA1CA2
SCHEMBL28541741 0.72 HSP90AA1 (0.58) HSP90AA1CA1CA2CA4CA6
SCHEMBL24329683 0.72 HSP90AA1 (0.55) HSP90AA1CA1CA2CA4CA6
SCHEMBL5579139 0.69 HSD11B1 (0.40) NPC1RAB9AKMT2AMEN1USP2
SCHEMBL1922789 0.68 METAP1 (0.57) HSP90AA1CA1CA2CA4CA6
SCHEMBL29572171 0.68 METAP1 (0.57) HSP90AA1CA1CA2CA4CA6
SCHEMBL29068479 0.68 NPC1 (0.52) NPC1RAB9AACHEKMT2AMEN1
SCHEMBL11794571 0.68 MAPT (0.49) HSP90AA1NPC1RAB9AKMT2AMEN1
SCHEMBL1921628 0.67 KDM4E (0.59) HSP90AA1NPC1RAB9ACA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0559525-A2 Thermal printing medium and method for preparing the same TOMOEGAWA PAPER CO. LTD. (JP) 1993-09-08 EP disclosed