SCHEMBL24329683

SCHEMBL24329683

CBc1cccc2c1Cc1cc(Cl)ccc1-2

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 2/20 0.55
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA4 P22748 1/20 0.42
CA6 P23280 1/20 0.42
ACHE P22303 2/20 0.39
METAP1 P53582 1/20 0.38
PGR P06401 1/20 0.35
CYP1A2 P05177 1/20 0.35
ITGA1 P56199 1/20 0.33
SRD5A1 P18405 1/20 0.33
SRD5A2 P31213 1/20 0.33
CMA1 P23946 1/20 0.33
AHR P35869 1/20 0.33
CYP2D6 P10635 1/20 0.32
HRH1 P35367 1/20 0.32
KCNH2 Q12809 1/20 0.32
CNR1 P21554 1/20 0.32
DRD2 P14416 1/20 0.32
DRD4 P21917 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24384111 0.80 PNMT (0.49) CA1CA2CA4CA6PGR
SCHEMBL28941745 0.79 HSP90AA1 (0.59) HSP90AA1CA1CA2CA4CA6
SCHEMBL25720295 0.78 HSP90AA1 (0.38) HSP90AA1CA1CA2CA4CA6
SCHEMBL25720243 0.72 DRD2 (0.40) HSP90AA1METAP1CYP1A2ITGA1CNR1
SCHEMBL28541741 0.72 HSP90AA1 (0.58) HSP90AA1CA1CA2CA4CA6
SCHEMBL9565535 0.72 HSP90AA1 (0.51) HSP90AA1CA1CA2CA4CA6
SCHEMBL29572171 0.71 METAP1 (0.57) HSP90AA1CA1CA2CA4CA6
SCHEMBL1922789 0.71 METAP1 (0.57) HSP90AA1CA1CA2CA4CA6
SCHEMBL1921628 0.70 KDM4E (0.59) HSP90AA1CA1CA2CA4CA6
SCHEMBL27565099 0.67 HSP90AA1 (0.46) HSP90AA1CA1CA2CA4CA6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3981762-A1 NITROGEN-CONTAINING COMPOUND, ELECTRONIC ELEMENT, AND ELECTRONIC DEVICE Shaanxi Lighte Optoelectronics Material Co., Ltd. (CN) 2022-04-13 EP disclosed