SCHEMBL9565549

SCHEMBL9565549

CCNc1cc(C)c(Nc2ccccc2)c2c1C(=O)OC21c2ccccc2Oc2ccccc21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.38
ALOX12 P18054 2/20 0.38
ALDH1A1 P00352 1/20 0.38
CYP2C9 P11712 1/20 0.38
ALOX15 P16050 1/20 0.38
BRCA1 P38398 1/20 0.38
HSD17B10 Q99714 1/20 0.38
CYP3A4 P08684 1/20 0.33
FTO Q9C0B1 3/20 0.32
MAPT P10636 2/20 0.32
MEN1 O00255 1/20 0.32
CYP2C19 P33261 1/20 0.32
HTT P42858 1/20 0.32
RECQL P46063 1/20 0.32
BLM P54132 1/20 0.32
SMAD3 P84022 1/20 0.32
KMT2A Q03164 1/20 0.32
PRMT1 Q99873 1/20 0.32
ACE2 Q9BYF1 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL548194 0.90 CYP2C9 (0.36) HPGDALOX12ALDH1A1CYP2C9ALOX15
SCHEMBL339448 0.89 TLR8 (0.36) HPGDALOX12ALDH1A1CYP2C9ALOX15
SCHEMBL3970970 0.89 HPGD (0.38) HPGDALOX12ALDH1A1CYP2C9ALOX15
SCHEMBL6537056 0.89 HPGD (0.40) HPGDALOX12ALDH1A1CYP2C9ALOX15
SCHEMBL4077129 0.88 ALDH1A1 (0.35) HPGDALOX12ALDH1A1CYP2C9ALOX15
SCHEMBL8377764 0.87 ALDH1A1 (0.34) HPGDALOX12ALDH1A1CYP2C9ALOX15
SCHEMBL11003355 0.87 HPGD (0.39) HPGDALOX12ALDH1A1CYP2C9ALOX15
SCHEMBL9845551 0.86 CHRM2 (0.35) HPGDALOX12ALDH1A1CYP2C9ALOX15
SCHEMBL395637 0.85 ALDH1A1 (0.35) HPGDALOX12ALDH1A1CYP2C9ALOX15
SCHEMBL10434777 0.85 HPGD (0.37) HPGDALOX12ALDH1A1CYP2C9ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0165041-B1 RECORD MATERIAL APPLETON PAPERS INC. (US) 1989-01-04 EP claimed
EP-0189760-A1 Thermosensitive recording sheet JUJO PAPER CO., LTD. (JP) 1986-08-06 EP claimed
EP-0559525-A2 Thermal printing medium and method for preparing the same TOMOEGAWA PAPER CO. LTD. (JP) 1993-09-08 EP disclosed
EP-0414229-A2 Heat-sensitive recording material NEW OJI PAPER CO., LTD. (JP) 1991-02-27 EP disclosed
EP-0245836-A2 Thermosensitive recording sheet DAINIPPON INK AND CHEMICALS, INC. (JP) 1987-11-19 EP disclosed