SCHEMBL3970970

SCHEMBL3970970

CCNc1cc(Cl)c(Nc2ccccc2)c2c1C(=O)OC21c2ccccc2Oc2ccccc21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.38
ALDH1A1 P00352 2/20 0.38
CYP2C9 P11712 1/20 0.38
ALOX15 P16050 1/20 0.38
ALOX12 P18054 1/20 0.38
BRCA1 P38398 1/20 0.38
HSD17B10 Q99714 1/20 0.38
PGR P06401 3/20 0.34
CYP3A4 P08684 1/20 0.33
CXCR2 P25025 4/20 0.32
MAPT P10636 2/20 0.32
FTO Q9C0B1 2/20 0.32
MEN1 O00255 1/20 0.32
CYP2C19 P33261 1/20 0.32
HTT P42858 1/20 0.32
RECQL P46063 1/20 0.32
BLM P54132 1/20 0.32
SMAD3 P84022 1/20 0.32
KMT2A Q03164 1/20 0.32
PRMT1 Q99873 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27905 0.91 KDM4E (0.37) HPGDALDH1A1CYP2C9ALOX15ALOX12
SCHEMBL9565549 0.89 HPGD (0.38) HPGDALDH1A1CYP2C9ALOX15ALOX12
SCHEMBL5681927 0.84 ALDH1A1 (0.36) HPGDALDH1A1CYP2C9ALOX15ALOX12
SCHEMBL16430376 0.84 ALDH1A1 (0.38) HPGDALDH1A1CYP2C9ALOX15ALOX12
SCHEMBL4659426 0.82 ALOX15 (0.41) HPGDALDH1A1CYP2C9ALOX15ALOX12
SCHEMBL10868252 0.81 ALDH1A1 (0.36) HPGDALDH1A1CYP2C9ALOX15ALOX12
SCHEMBL548194 0.80 CYP2C9 (0.36) HPGDALDH1A1CYP2C9ALOX15ALOX12
SCHEMBL339448 0.79 TLR8 (0.36) HPGDALDH1A1CYP2C9ALOX15ALOX12
SCHEMBL11035507 0.78 BRCA1 (0.35) HPGDALDH1A1CYP2C9ALOX15ALOX12
SCHEMBL10434777 0.78 HPGD (0.37) HPGDALDH1A1CYP2C9ALOX15ALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2054769-A1 UV-DOSIS INDICATORS Ciba Holding Inc. (CH) 2009-05-06 EP disclosed
WO-2008022952-A1 UV-DOSIS INDICATORS CIBA HOLDING INC. (CH) 2008-02-28 WO disclosed
EP-1751220-A1 METHOD OF COLORING A COATING COMPOSITION CIBA SPECIALTY CHEMICALS HOLDING INC. Patent Departement (CH) 2007-02-14 EP disclosed
WO-2005097876-A1 METHOD OF COLORING A COATING COMPOSITION CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2005-10-20 WO disclosed