Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.40 |
| ▸ | MERTK | Q12866 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9565652 | 0.81 | KDM4E (0.51) | KDM4ETDP1MAPK1L3MBTL1NPC1 | |
| SCHEMBL11187544 | 0.77 | KDM4E (0.53) | KDM4ETDP1MAPK1L3MBTL1NPC1 | |
| SCHEMBL6307067 | 0.77 | HSP90AA1 (0.69) | MAPK1ALDH1A1HSP90AA1SMN1; SMN2 | |
| SCHEMBL1704219 | 0.77 | KDM4E (0.69) | KDM4ETDP1MAPK1L3MBTL1NPC1 | |
| SCHEMBL9565642 | 0.75 | L3MBTL1 (0.52) | KDM4ETDP1MAPK1L3MBTL1NPC1 | |
| SCHEMBL5846199 | 0.73 | KDM4E (0.52) | KDM4ETDP1MAPK1L3MBTL1NPC1 | |
| SCHEMBL1780998 | 0.73 | KDM4E (0.56) | KDM4ETDP1MAPK1L3MBTL1NPC1 | |
| SCHEMBL322756 | 0.73 | KDM4E (1.00) | KDM4ETDP1MAPK1L3MBTL1NPC1 | |
| SCHEMBL29354466 | 0.73 | KDM4E (1.00) | KDM4ETDP1MAPK1L3MBTL1NPC1 | |
| SCHEMBL3573674 | 0.72 | LMNA (0.50) | KDM4EMAPK1L3MBTL1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5240926-A | Fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1993-08-31 | — | — | US | disclosed |
| EP-0529468-A1 | Substituted pyridyltriazines, process for their preparation, their use and intermediates | BAYER AG (DE) | 1993-03-03 | — | — | EP | disclosed |