Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | GRM5 | P41594 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9565642 | 0.86 | L3MBTL1 (0.52) | KDM4ETDP1FFAR1HSP90AA1HSP90AB1 | |
| SCHEMBL9565604 | 0.81 | KDM4E (0.53) | KDM4ETDP1FFAR1HSP90AA1L3MBTL1 | |
| SCHEMBL9565651 | 0.81 | KDM4E (0.56) | KDM4ETDP1FFAR1L3MBTL1GRM5 | |
| SCHEMBL9565619 | 0.80 | KDM4E (0.51) | KDM4ETDP1FFAR1HSP90AA1L3MBTL1 | |
| SCHEMBL12974970 | 0.77 | KMT2A (0.57) | KDM4EL3MBTL1ALDH1A1HTTKMT2A | |
| SCHEMBL9565645 | 0.77 | KDM4E (0.55) | KDM4ETDP1FFAR1L3MBTL1GRM5 | |
| SCHEMBL11187544 | 0.76 | KDM4E (0.53) | KDM4ETDP1HSP90AA1HSP90AB1L3MBTL1 | |
| SCHEMBL1704219 | 0.76 | KDM4E (0.69) | KDM4ETDP1HSP90AA1HSP90AB1L3MBTL1 | |
| SCHEMBL12628228 | 0.75 | KDM4E (0.67) | KDM4ETDP1L3MBTL1GRM5ALDH1A1 | |
| SCHEMBL22043746 | 0.75 | TP53 (0.67) | KDM4ETDP1L3MBTL1GRM5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5240926-A | Fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1993-08-31 | — | — | US | disclosed |
| EP-0529468-A1 | Substituted pyridyltriazines, process for their preparation, their use and intermediates | BAYER AG (DE) | 1993-03-03 | — | — | EP | disclosed |