Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | GRM5 | P41594 | 4/20 | 0.47 |
| ▸ | TGFBR1 | P36897 | 4/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | F12 | P00748 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18905446 | 0.86 | KDM4E (0.63) | KDM4ETDP1RAB9ANPC1TP53 | |
| SCHEMBL3616834 | 0.84 | KDM4E (0.77) | KDM4ETDP1RAB9ANPC1GRM5 | |
| SCHEMBL27799881 | 0.82 | DPP4 (0.46) | RAB9ANPC1MEN1KMT2AATM | |
| SCHEMBL16197571 | 0.82 | RAB9A (0.50) | RAB9ANPC1TP53MEN1KMT2A | |
| SCHEMBL22043746 | 0.81 | TP53 (0.67) | KDM4ETDP1RAB9ANPC1GRM5 | |
| SCHEMBL9565651 | 0.81 | KDM4E (0.56) | KDM4ETDP1RAB9ANPC1GRM5 | |
| SCHEMBL29084765 | 0.79 | KDM4E (0.53) | KDM4ETDP1RAB9ANPC1TP53 | |
| SCHEMBL25886498 | 0.79 | KDM4E (0.53) | KDM4ETDP1RAB9ANPC1TP53 | |
| SCHEMBL17229050 | 0.79 | KDM4E (0.53) | KDM4ETDP1RAB9ANPC1GRM5 | |
| SCHEMBL1358217 | 0.78 | TGFBR1 (0.57) | KDM4ETDP1RAB9ANPC1GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5240926-A | Fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1993-08-31 | — | — | US | disclosed |
| EP-0529468-A1 | Substituted pyridyltriazines, process for their preparation, their use and intermediates | BAYER AG (DE) | 1993-03-03 | — | — | EP | disclosed |