Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | EGFR | P00533 | 1/20 | 0.53 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.53 |
| ▸ | IGF1R | P08069 | 1/20 | 0.53 |
| ▸ | CTRC | Q99895 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | EEF2K | O00418 | 1/20 | 0.48 |
| ▸ | SRC | P12931 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9565720 | 1.00 | ALDH1A1 (0.56) | ALDH1A1MAPTKDM4EHPGDNPSR1 | |
| SCHEMBL9565774 | 0.86 | MAPT (0.43) | ALDH1A1MAPTKDM4EHPGDNPSR1 | |
| SCHEMBL9565770 | 0.86 | MAPT (0.43) | ALDH1A1MAPTKDM4EHPGDNPSR1 | |
| SCHEMBL9565732 | 0.75 | EEF2K (0.57) | ALDH1A1EGFRERBB2IGF1RGAA | |
| SCHEMBL21239495 | 0.74 | MAPT (0.70) | ALDH1A1MAPTKDM4EHPGDNPSR1 | |
| SCHEMBL21239493 | 0.74 | MAPT (0.70) | ALDH1A1MAPTKDM4EHPGDNPSR1 | |
| SCHEMBL13045105 | 0.74 | GAA (0.75) | ALDH1A1EGFRERBB2IGF1RCTRC | |
| SCHEMBL9565701 | 0.73 | MAPT (0.68) | ALDH1A1MAPTKDM4EHPGDEGFR | |
| SCHEMBL9565700 | 0.73 | MAPT (0.68) | ALDH1A1MAPTKDM4EHPGDEGFR | |
| SCHEMBL21239435 | 0.72 | KMT2A (0.60) | ALDH1A1MAPTKDM4EHPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0546661-A1 | Pyrimidine derivatives, method for preparation thereof and pharmaceutical composition having said derivatives as active elements | JAPAN ENERGY CORPORATION (JP) | 1993-06-16 | — | — | EP | disclosed |