Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | CTRC | Q99895 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.37 |
| ▸ | EEF2K | O00418 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9565774 | 1.00 | MAPT (0.43) | MAPTALDH1A1NPSR1KDM4EHPGD | |
| SCHEMBL9565720 | 0.86 | ALDH1A1 (0.56) | MAPTALDH1A1NPSR1KDM4EHPGD | |
| SCHEMBL9565719 | 0.86 | ALDH1A1 (0.56) | MAPTALDH1A1NPSR1KDM4EHPGD | |
| SCHEMBL9565714 | 0.83 | MEN1 (0.55) | MAPTALDH1A1NPSR1KDM4EHPGD | |
| SCHEMBL9565715 | 0.83 | MEN1 (0.55) | MAPTALDH1A1NPSR1KDM4EHPGD | |
| SCHEMBL9565718 | 0.83 | EEF2K (0.51) | MAPTALDH1A1MEN1KMT2AEGFR | |
| SCHEMBL9565732 | 0.69 | EEF2K (0.57) | ALDH1A1MEN1KMT2AEGFRERBB2 | |
| SCHEMBL9565701 | 0.65 | MAPT (0.68) | MAPTALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL9565700 | 0.65 | MAPT (0.68) | MAPTALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL8583755 | 0.64 | CYP1A2 (0.44) | ALDH1A1MEN1KMT2AGAAPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0546661-A1 | Pyrimidine derivatives, method for preparation thereof and pharmaceutical composition having said derivatives as active elements | JAPAN ENERGY CORPORATION (JP) | 1993-06-16 | — | — | EP | disclosed |