Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.55 |
| ▸ | RAB9A | P51151 | 6/20 | 0.55 |
| ▸ | PKM | P14618 | 3/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.52 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.52 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17620897 | 0.79 | NPC1 (0.49) | NPC1RAB9APKMADRA2AADRA2B | |
| SCHEMBL2782158 | 0.79 | NPC1 (0.49) | NPC1RAB9APKMADRA2AADRA2B | |
| SCHEMBL25857032 | 0.79 | RAB9A (0.58) | NPC1RAB9APKMADRA2AADRA2B | |
| SCHEMBL525427 | 0.76 | RAB9A (0.61) | NPC1RAB9APKMGAASMN1; SMN2 | |
| SCHEMBL10793724 | 0.76 | RAB9A (0.59) | NPC1RAB9APKMGAASMN1; SMN2 | |
| SCHEMBL29399796 | 0.76 | RAB9A (0.61) | NPC1RAB9APKMGAASMN1; SMN2 | |
| SCHEMBL438214 | 0.76 | RAB9A (0.70) | NPC1RAB9APKMGAASMN1; SMN2 | |
| SCHEMBL2226467 | 0.76 | RAB9A (0.59) | NPC1RAB9APKMGAASMN1; SMN2 | |
| SCHEMBL1486005 | 0.76 | NPC1 (0.63) | NPC1RAB9APKMGAASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL31091390 | 0.74 | RAB9A (0.59) | NPC1RAB9APKMGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5211740-A | Applying triazinyl sulfonylguanidine derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1993-05-18 | — | — | US | claimed |
| EP-0529292-A2 | Substituted aralkylsulfonyl-aminoguanidinoazines as herbizides | BAYER AG (DE) | 1993-03-03 | — | — | EP | claimed |
| US-5092917-A | HERBICIDAL AMINOGUANIDINOAZINES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-03-03 | — | — | US | claimed |
| EP-0343462-B1 | AMINOGUANIDINO AZINES | BAYER AG (DE) | 1991-12-11 | — | — | EP | claimed |
| EP-0414067-A2 | Substituted arylsulfonyl-aminoguanidinoazine | BAYER AG (DE) | 1991-02-27 | — | — | EP | claimed |
| EP-0343462-A1 | Aminoguanidino azines | BAYER AG (DE) | 1989-11-29 | — | — | EP | claimed |
| EP-0530616-A1 | Pyrazolylsulfonylguanidino pyrimidines as herbicides | BAYER AG (DE) | 1993-03-10 | — | — | EP | disclosed |
| EP-0529292-A2 | Substituted aralkylsulfonyl-aminoguanidinoazines as herbizides | BAYER AG (DE) | 1993-03-03 | — | — | EP | disclosed |
| EP-0343462-B1 | AMINOGUANIDINO AZINES | BAYER AG (DE) | 1991-12-11 | — | — | EP | disclosed |
| EP-0343462-B1 | AMINOGUANIDINO AZINES | BAYER AG (DE) | 1991-12-11 | — | — | EP | disclosed |
| EP-0431270-A1 | Substituted sulfonylamidinohydrazones | BAYER AG (DE) | 1991-06-12 | — | — | EP | disclosed |
| EP-0414067-A2 | Substituted arylsulfonyl-aminoguanidinoazine | BAYER AG (DE) | 1991-02-27 | — | — | EP | disclosed |
| EP-0343462-A1 | Aminoguanidino azines | BAYER AG (DE) | 1989-11-29 | — | — | EP | disclosed |
| EP-0343462-A1 | Aminoguanidino azines | BAYER AG (DE) | 1989-11-29 | — | — | EP | disclosed |
| EP-0302378-A2 | Sulphonylaminoguanidino azines | BAYER AG (DE) | 1989-02-08 | — | — | EP | disclosed |