SCHEMBL9565758

SCHEMBL9565758

Brc1ccc2c(c1)SCC2c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 1/20 0.39
SIRT2 Q8IXJ6 2/20 0.35
KDM1A O60341 4/20 0.35
MEN1 O00255 1/20 0.35
NPC1 O15118 1/20 0.35
KMT2A Q03164 1/20 0.35
SIRT1 Q96EB6 1/20 0.35
HTR2A P28223 5/20 0.34
HTR2C P28335 5/20 0.34
HTR2B P41595 4/20 0.34
HRH3 Q9Y5N1 4/20 0.34
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33
HDAC4 P56524 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24011655 0.87 CYP19A1 (0.39) CYP19A1SIRT2KDM1AMEN1NPC1
SCHEMBL9565765 0.78 MEN1 (0.44) MEN1NPC1KMT2A
SCHEMBL12501491 0.72 KDM1A (0.41) KDM1AHTR2AHTR2CSLC6A2SLC6A4
SCHEMBL31705254 0.72 KDM1A (0.41) KDM1AHTR2AHTR2CSLC6A2SLC6A4
SCHEMBL6089022 0.72 KDM1A (0.33) KDM1A
SCHEMBL12291661 0.71 SIRT2 (0.37) SIRT2KDM1AMEN1KMT2ASLC6A2
SCHEMBL14488047 0.70 HTR2A (0.46) CYP19A1SIRT2KDM1AMEN1NPC1
SCHEMBL9565761 0.70 TRPM5 (0.40) CYP19A1KDM1AMEN1NPC1KMT2A
SCHEMBL12290951 0.68 ALDH1A1 (0.35) MEN1KMT2ASLC6A2SLC6A4
SCHEMBL12290970 0.68 SIRT2 (0.40) SIRT2KDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0526951-A1 3-Phenyl benzo b thiophenes as pesticidal compounds SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1993-02-10 EP disclosed