Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM5 | Q9NZQ8 | 3/20 | 0.40 |
| ▸ | TRPM4 | Q8TD43 | 2/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 4/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 3/20 | 0.35 |
| ▸ | DRD4 | P21917 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24011655 | 0.80 | CYP19A1 (0.39) | CYP19A1MEN1KMT2AKDM1ANPC1 | |
| SCHEMBL9565765 | 0.78 | MEN1 (0.44) | MEN1KMT2ANPC1CYP3A4CYP2D6 | |
| SCHEMBL24011657 | 0.73 | LIPG (0.43) | — | |
| SCHEMBL9565758 | 0.70 | CYP19A1 (0.39) | CYP19A1MEN1KMT2AKDM1AHTR2C | |
| SCHEMBL6055982 | 0.68 | DRD2 (0.49) | CYP19A1DRD2DRD1KDM1AMAOA | |
| SCHEMBL2070013 | 0.68 | DRD2 (0.49) | CYP19A1DRD2DRD1KDM1AMAOA | |
| SCHEMBL8885782 | 0.68 | DRD2 (0.46) | TRPM5TRPM4CYP19A1DRD2DRD1 | |
| SCHEMBL2152822 | 0.68 | DRD2 (0.49) | CYP19A1DRD2DRD1KDM1AMAOA | |
| SCHEMBL14781250 | 0.68 | HTR2C (0.44) | DRD2HRH1DRD4HTR2CNPC1 | |
| SCHEMBL13373462 | 0.68 | HTR2C (0.38) | HTR2CCYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0526951-A1 | 3-Phenyl benzo b thiophenes as pesticidal compounds | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1993-02-10 | — | — | EP | disclosed |