SCHEMBL9565841

SCHEMBL9565841

CCCCCCCC(=O)N1CCN(c2ccccc2Cl)CC1

nearest known ligand 0.60

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.60
KDM4E B2RXH2 1/20 0.60
HTR7 P34969 1/20 0.57
MAPT P10636 4/20 0.57
MEN1 O00255 3/20 0.57
KMT2A Q03164 3/20 0.57
TSHR P16473 2/20 0.57
ALDH1A1 P00352 2/20 0.55
NPSR1 Q6W5P4 1/20 0.55
AR P10275 1/20 0.53
GRM5 P41594 1/20 0.53
ADAMTS5 Q9UNA0 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.52
GNAI3 P08754 1/20 0.51
GNAI1 P63096 1/20 0.51
GSK3B P49841 3/20 0.51
CNR1 P21554 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9565914 1.00 LMNA (0.60) LMNAKDM4EHTR7MAPTMEN1
SCHEMBL9565882 0.91 CNR1 (0.66) LMNAKDM4EHTR7MAPTMEN1
SCHEMBL9565884 0.91 CNR1 (0.66) LMNAKDM4EHTR7MAPTMEN1
SCHEMBL1375794 0.86 KMT2A (0.53) LMNAHTR7MAPTMEN1KMT2A
SCHEMBL1376551 0.86 KMT2A (0.53) LMNAHTR7MAPTMEN1KMT2A
SCHEMBL12431991 0.86 HTR7 (0.54) LMNAHTR7MAPTMEN1KMT2A
SCHEMBL1376636 0.84 HDAC1 (0.67) LMNAHTR7MAPTMEN1KMT2A
SCHEMBL1374622 0.84 HDAC1 (0.67) LMNAHTR7MAPTMEN1KMT2A
SCHEMBL28523079 0.83 HTR1A (0.67) LMNAHTR7MEN1KMT2ATSHR
SCHEMBL28907245 0.83 HTR1A (0.67) LMNAHTR7MEN1KMT2ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0548798-A1 Antiviral agent SANWA KAGAKU KENKYUSHO CO., LTD. (JP) 1993-06-30 EP disclosed